Biodegradable ceramics consisting of hydroxyapatite for orthopaedic implants

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dc.contributor.authorMonsees, Thomas K.
dc.contributor.authorAzem, Funda Ak
dc.contributor.authorCotrut, Cosmin Mihai
dc.contributor.authorBraic, Mariana
dc.contributor.authorAbdulgader, Radwan
dc.contributor.authorPana, Iulian
dc.contributor.authorBirlik, Isil
dc.contributor.authorKiss, Adrian
dc.contributor.authorBooysen, Robin
dc.contributor.authorVladescu, Alina
dc.date.accessioned2017-11-07T12:38:10Z
dc.date.available2017-11-07T12:38:10Z
dc.date.issued2017
dc.description.abstractThis study aims to analyze hydroxyapatite (HAP) coatings enriched with Mg and Ti prepared by a magnetron sputtering technique on Ti6Al4V substrate. For preparation of the coatings, three magnetron targets (HAP, MgO and TiO2) were simultaneously co-worked. The concentration of Mg added was varied by modifying the power applied to the MgO target. In all coatings, the Ti concentration was maintained constant by keeping the same cathode power fed during the whole deposition. The influence of different Mg dopant contents on the formation of phase, microstructure and morphology of the obtained Ti-doped HAP coatings were characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). Moreover, the effects of Mg addition upon corrosion, mechanical and biological properties were also investigated. Mg- and Ti-doped HAP coating obtained at low radio-frequency (RF) power fed to the MgO target provided material with high corrosion resistance compared to other coatings and bare alloy. A slight decrease in hardness of the coatings was found after the Mg addition, from 8.8 to 5.7 GPa. Also, the values of elastic modulus were decreased from 87 to 53 GPa, this being an advantage for biomedical applications. The coatings with low Mg concentration proved to have good deformation to yielding and higher plastic properties. Biological test results showed that the novel surfaces exhibited excellent properties for the adhesion and growth of bone cells. Moreover, early adherent vital cell numbers were significantly higher on both coatings compared to Ti6Al4V, suggesting that Mg ions may accelerate initial osteoblast adhesion and proliferation.en_US
dc.identifier.citationMonsees, T.K. et al. (2017). Biodegradable ceramics consisting of hydroxyapatite for orthopaedic implants. Coatings, 7(11): 184en_US
dc.identifier.issn2079-6412
dc.identifier.urihttp://dx.doi/org/10.3390/coatings7110184
dc.identifier.urihttp://hdl.handle.net/10566/3257
dc.language.isoenen_US
dc.privacy.showsubmitterFALSE
dc.publisherMDPIen_US
dc.rights© 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
dc.status.ispeerreviewedTRUE
dc.subjectHydroxyapatiteen_US
dc.subjectCorrosionen_US
dc.subjectRoughnessen_US
dc.subjectNanoindentationen_US
dc.subjectOsteoblastsen_US
dc.subjectMagnetron sputteringen_US
dc.titleBiodegradable ceramics consisting of hydroxyapatite for orthopaedic implantsen_US
dc.typeArticleen_US

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