The Ism between endothelial cilia and endothelial nanotubules is an evolving concept in the genesis of the BBB

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dc.contributor.authorMentor, Shireen
dc.contributor.authorFisher, David
dc.date.accessioned2022-09-19T09:49:29Z
dc.date.available2022-09-19T09:49:29Z
dc.date.issued2022
dc.description.abstractThe blood–brain barrier (BBB) is fundamental in maintaining central nervous system (CNS) homeostasis by regulating the chemical environment of the underlying brain parenchyma. Brain endothelial cells (BECs) constitute the anatomical and functional basis of the BBB. Communication between adjacent BECs is critical for establishing BBB integrity, and knowledge of its nanoscopic landscape will contribute to our understanding of how juxtaposed zones of tight-junction protein interactions between BECs are aligned. The review discusses and critiques types of nanostructures contributing to the process of BBB genesis. We further critically evaluate earlier findings in light of novel high-resolution electron microscopy descriptions of nanoscopic tubules.en_US
dc.identifier.citationMentor, S., & Fisher, D. (2022). The Ism between endothelial cilia and endothelial nanotubules is an evolving concept in the genesis of the BBB. International Journal of Molecular Sciences, 23(5), 2457. https://doi.org/10.3390/ijms23052457en_US
dc.identifier.issn1422-0067
dc.identifier.urihttps://doi.org/10.3390/ijms23052457
dc.identifier.urihttp://hdl.handle.net/10566/7912
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.subjectBrain endotheliumen_US
dc.subjectNanotubulesen_US
dc.subjectCentral nervous systemen_US
dc.subjectBioscienceen_US
dc.titleThe Ism between endothelial cilia and endothelial nanotubules is an evolving concept in the genesis of the BBBen_US
dc.typeArticleen_US

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