Crataegus monogyna and centella asiatica extracts as inhibitors of cathepsin s

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dc.contributor.authorObikeze, Kenechukwu
dc.contributor.authorGainsford, Garth
dc.contributor.authorKamaar, Maajidah
dc.date.accessioned2022-09-21T09:24:24Z
dc.date.available2022-09-21T09:24:24Z
dc.date.issued2022
dc.description.abstractCathepsin cysteine proteases such as cathepsin S are responsible for the unfavorable and irreversible dysregulation of extracellular matrix (ECM) proteolysis found in cardiomyopathy, heart valve diseases and atherosclerosis. Cathepsin S plays a central role in ECM remodeling, which has been implicated in the development and progression of cardiovascular diseases. The current study aimed to evaluate the aqueous and ethanol extracts of the berries of Crataegus monogyna and the leaves of Centella asiatica for inhibition of cathepsin S activity using an in vitro fluorescent assay.en_US
dc.identifier.citationObikeze, K. et al. (2022). Crataegus monogyna and centella asiatica extracts as inhibitors of cathepsin s. Advances in Pharmacology and Pharmacy, 10(4), 247-252. 10.13189/app.2022.100403en_US
dc.identifier.issn2332-0044
dc.identifier.uri10.13189/app.2022.100403
dc.identifier.urihttp://hdl.handle.net/10566/7938
dc.language.isoenen_US
dc.publisherHorizon Research Publishingen_US
dc.subjectCrataegus monogynaen_US
dc.subjectCathepsin Sen_US
dc.subjectCardiovascular diseaseen_US
dc.subjectCentella asiaticaen_US
dc.subjectPharmacologyen_US
dc.titleCrataegus monogyna and centella asiatica extracts as inhibitors of cathepsin sen_US
dc.typeArticleen_US

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