Systematic approach to protein crystallization: emphasis on Vaccinia virus complement control protein (VCP)
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Date
2006
Authors
Journal Title
Journal ISSN
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Publisher
University of the Western Cape
Abstract
This work examined the systematic approach to protein crystallization, exploring some of the techniques that have been developed to enhance the success rate of crystallization. The work was centered on two proteins; namely Vaccinia virus complement control protein (VCP) and glutamate dehydrogenase (GDH) from Bacteriodes fragilis. The crystal structures of the full lengthe native VCP and VCP bound to heparin had already been determined. In the same way, the structure of GDH from Bacteriodes fragilis is not known, even though structures of other GDHs from different organisms have been determined.
Description
Magister Scientiae - MSc
Keywords
Crystallization, Crystal growth