Coding of tsetse repellents by olfactory sensory neurons: towards the improvement and the development of novel tsetse repellents

dc.contributor.advisorChristoffels, Alan
dc.contributor.authorSouleymane, Diallo
dc.date.accessioned2021-03-25T09:06:59Z
dc.date.accessioned2024-05-17T07:57:43Z
dc.date.available2021-03-25T09:06:59Z
dc.date.available2024-05-17T07:57:43Z
dc.date.issued2021
dc.descriptionPhilosophiae Doctor - PhDen_US
dc.description.abstractTsetse flies are the biological vectors of human and animal trypanosomiasis and hence representant medical and veterinary importance. The sense of smell plays a significant role in tsetse and its ecological interaction, such as finding blood meal source, resting, and larvicidal sites and for mating. Tsetse olfactory behaviour can be exploited for their management; however, olfactory studies in tsetse flies are still fragmentary. Here in my PhD thesis, using scanning electron microscopy, electrophysiology, behaviour, bioinformatics and molecular biology techniques, I have investigated tsetse flies (Glossina fuscipes fuscipes) olfaction using behaviourally well studied odorants, tsetse repellent by comparing with attractant odour. Insect olfaction is mediated by olfactory sensory neurons (OSNs), located in olfactory sensilla, which are cuticular structures exposed to the environment through pore and create a platform for chemical communication.en_US
dc.identifier.urihttps://hdl.handle.net/10566/15265
dc.language.isoenen_US
dc.publisherUniversity of Western Capeen_US
dc.rights.holderUniversity of Western Capeen_US
dc.subjectGlossina fuscipes fuscipesen_US
dc.subjectFeeding deterrenceen_US
dc.subjectOlfactory sensory neuronsen_US
dc.subjectChemosensory proteinsen_US
dc.subjectOdorant receptors deorphanizationen_US
dc.titleCoding of tsetse repellents by olfactory sensory neurons: towards the improvement and the development of novel tsetse repellentsen_US

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