Antimicrobial resistant Gram-positive cocci in pregnant mothers with aerobic vaginitis

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dc.contributor.authorKaambo, Eveline
dc.contributor.authorAbrantes, Pedro Miguel dos Santos
dc.contributor.authorMcArthur, Carole P.
dc.contributor.authorAfrica, Charlene W.J.
dc.date.accessioned2016-10-07T13:24:41Z
dc.date.available2016-10-07T13:24:41Z
dc.date.issued2016
dc.description.abstractThe vaginal microbiota of a healthy asymptomatic woman consists of an extensive diversity of anaerobic and aerobic bacterial genera and species dominated by the microaerophilic genus Lactobacillus , known to inhibit the growth of potentially pathogenic non-acid tolerant microorganisms. An imbalance of species within this biofilm may result in endogenous opportunistic infections such as aerobic vaginitis (AV) caused by S. agalactiae and E. faecalis, which have been implicated in neonatal and obstetric sepsis. The prevalence and antimicrobial susceptibility of E. faecalis and S. agalactiae in pregnant women with AV in the Western Cape, South Africa was determined using standard microbiological culture methods and the Sensititre TREK system. AV was detected in 26.13% of the 199 tested pregnant women, with S. agalactiae and E. faecalis isolated from 32 and 20 mothers respectively. S. agalactiae and E. faecalis showed resistance to 12 of the 17 antibiotics tested, including those recommended for prophylaxis according to the CDC guidelines. The resistance of S. agalactiae and E. faecalis to commonly administered antimicrobials highlights the need for alternative treatment regimens for AV during pregnancy to reduce the risk of AV-associated negative pregnancy outcomes.en_US
dc.description.sponsorshipNational Research Foundation of South Africaen_US
dc.identifier.citationKaambo, E. et al. (2016). Antimicrobial resistant Gram-positive cocci in pregnant mothers with aerobic vaginitis. Poster presented at the 6th Infection Control Africa Network Congress, (25-28 September), Johannesburgen_US
dc.identifier.urihttp://hdl.handle.net/10566/2442
dc.language.isoenen_US
dc.publisherInfection Control Africa Network (ICAN)en_US
dc.rightsUniversity of the Western Cape
dc.subjectAerobic vaginitisen_US
dc.subjectDrug resistanceen_US
dc.subjectPregnancy outcomesen_US
dc.titleAntimicrobial resistant Gram-positive cocci in pregnant mothers with aerobic vaginitisen_US
dc.typePresentationen_US

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