Do lifestyle practices impede male fertility?

dc.contributor.authorLeisegang, Kristian
dc.contributor.authorDutta, Sulagna
dc.date.accessioned2020-11-17T12:41:22Z
dc.date.available2020-11-17T12:41:22Z
dc.date.issued2020
dc.description.abstractAlongside an increasing prevalence of couple and male infertility, evidence suggests there is a global declining trend in male fertility parameters over the past few decades. This may, at least in part, be explained through detrimental lifestyle practices and exposures. These include alcohol and tobacco consumption, use of recreational drugs (e.g., cannabis, opioids and anabolic steroids), poor nutritional habits, obesity and metabolic syndrome, genital heat stress (e.g., radiation exposure through cell phones and laptops, prolonged periods of sitting, tight-fitting underwear and recurrent hot baths or saunas), exposure to endocrine-disrupting chemicals (e.g., pesticide residue, bisphenol A, phthalates and dioxins) and psychological stress. This review discusses these lifestyle practices and the current evidence associated with male infertility. Furthermore, known mechanisms of action are also discussed for each of these. Common mechanisms associated with a reduction in spermatogenesis and/ or steroidogenesis due to unfavourable lifestyle practices include inflammation and oxidative stress locally or systemically. It is recommended that relevant lifestyle practices are investigated in clinical history of male infertility cases, particularly in unexplained or idiopathic male infertility. Appropriate modification of detrimental lifestyle practices is further suggested and recommended in the management of male infertility.en_US
dc.identifier.citationLeisegang, K., & Dutta, S. (2020).Do lifestyle practices impede male fertility?. Andrologia, 52(11),e13595en_US
dc.identifier.issn1439-0272
dc.identifier.urihttps://doi.org/10.1111/and.13595
dc.identifier.urihttp://hdl.handle.net/10566/5440
dc.language.isoenen_US
dc.publisherJohn Wiley & Sons, Incen_US
dc.subjectEndocrine disruptorsen_US
dc.subjectGenital heat stressen_US
dc.subjectMale infertilityen_US
dc.subjectNutrition and obesityen_US
dc.subjectTobaccoen_US
dc.titleDo lifestyle practices impede male fertility?en_US
dc.typeArticleen_US

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