UniQ-Typer ™ Y-10 genotyping in South African populations: novel alleles, sequence variation and allelic ladder updates

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Date

2019

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

DNA profiling the male specific region on the Y-chromosome is fundamental to forensic practise. It is recognised as a powerful tool for sexual assault investigations for resolving the male DNA components, for familial search and as a tool to aid biogeographic inferences. In this study the novel Y-chromosome Short Tandem Repeat (Y-STR) multiplex called the UniQ-Typer ™ Y-10 was utilised for population wide genotyping in South Africa. In this study we provide a significant updated to the genotyping allelic ladder for the panel and report novel variation which gave strong signals to potentially infer biogeographic ancestry

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Keywords

DNA profiling, Y-chromosome, UniQ-Typer

Citation

Kasu, M., Fraser, M. and D’Amato, M.E. (2019) “Uniq-Typer ™ Y-10 genotyping in South African populations: Novel alleles, sequence variation and allelic ladder updates,” Forensic Science International: Genetics Supplement Series, 7(1), pp. 473–475. Available at: https://doi.org/10.1016/j.fsigss.2019.10.056.