In vitro antimicrobial comparison of three commercially available chlorhexidine-based oral rinses

dc.contributor.authorAbdalrahman, Basheer Mohamed
dc.contributor.authorHolmes, Haly
dc.contributor.authorPeck, Mogammad T.
dc.contributor.authorBasson, Nicolaas
dc.date.accessioned2018-05-23T09:30:33Z
dc.date.available2018-05-23T09:30:33Z
dc.date.issued2016
dc.description.abstractINTRODUCTION: Commercially available chlorhexidine (CHX) formulations differ in their CHX concentrations (0.2% and 0.12%) as well as in various additives including alcohol, antimicrobials such as cetylpyridinium chloride and antidiscolouration chemicals such as ascorbic acid and sodium metabisulphite. AIMS AND OBJECTIVES: To compare in vitro the antimicrobial efficacies of three different CHX preparations (Corsodyl ®, Curasept® and GUM® Paroex®) using 0.2% and 0.12% CHX concentrations as controls METHODS: A disk diffusion test was performed using pure cultures of the organisms Streptococcus mutans and Candida albicans, and mixed cultures (facultative and strict anaerobes) prepared from oral rinse samples of 14 study participants. The means and standard deviations of the diameters of inhibition zones were calculated. RESULTS: A statistically significant difference (p value = 0.0001) was found only in Candida albicans cultures between the mean inhibition zones of the CHX preparation disks. Pure CHX preparations and Corsodyl® showed higher antifungal efficacy than Curasept® and GUM® Paroex Conclusion: Both CHX preparations (0.12% and 0.2%) and the 0.2% CHX preparation containing alcohol (Corsodyl®) have more potent antifungal properties against C. albicans than alcohol-free 0.12% CHX preparations such as Curasept® and GUM® Paroex®.en_US
dc.description.accreditationDHET
dc.identifier.citationAbdalrahman, B.M. et al. (2016). In vitro antimicrobial comparison of three commercially available chlorhexidine-based oral rinses. South African Dentristry Journal, 71(7): 304 - 307en_US
dc.identifier.issn0375-1562
dc.identifier.urihttp://hdl.handle.net/10566/3725
dc.language.isoenen_US
dc.privacy.showsubmitterFALSE
dc.publisherSouth African Dental Associationen_US
dc.rightsThis file may be freely used for educational uses. No commercial reproduction or distribution of this file is permitted without written permission of the South African Dental Association (SADA). Note that the SADA retains all intellectual property rights in the article.
dc.status.ispeerreviewedTRUE
dc.subjectChlorhexidine (CHX)en_US
dc.subjectAntimicrobial efficaciesen_US
dc.subjectOral rinsesen_US
dc.titleIn vitro antimicrobial comparison of three commercially available chlorhexidine-based oral rinsesen_US
dc.typeArticleen_US

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