Determination of paracetamol at the electrochemically reduced graphene oxide-metal nanocomposite modified pencil graphite (ERGO-MC-PGE) electrode using adsorptive stripping differential pulse voltammetry

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Date

2020

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Publisher

University of Western Cape

Abstract

This project focuses on the development of simple, highly sensitive, accurate, and low cost electrochemical sensors based on the modification of pencil graphite electrodes by the electrochemical reduction of graphene oxide-metal salts as nanocomposites (ERGO-MC-PGE; MC = Sb or Au nanocomposite). The electrochemical sensors ERGO-Sb-PGE and ERGO-Au-PGE were used in the determination of paracetamol (PC) in pharmaceutical formulations using adsorptive stripping differential pulse voltammetry. The GO was prepared from graphite via a modified Hummers’ method and characterized by FTIR and Raman spectroscopy to confirm the presence of oxygen functional groups in the conjugated carbon-based structure whilst, changes in crystalline structure was observed after XRD analysis of graphite and GO.

Description

>Magister Scientiae - MSc

Keywords

Graphene oxide, Paracetamol, Pencil graphite electrode, Cyclic voltammetry, Graphene

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