A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa
| dc.contributor.author | Viljoen, Michelle | |
| dc.contributor.author | Rudman, Christian | |
| dc.contributor.author | Rheeders, Malie | |
| dc.date.accessioned | 2021-01-07T11:05:57Z | |
| dc.date.available | 2021-01-07T11:05:57Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | Greater access and prolonged exposure to ART may inevitably lead to more treatment failure and increase the need for third-line ART (TLART) in a resource-limited setting. Objective: To describe characteristics and resistance patterns of adult patients initiated on TLART in three districts of the North West province. Method: All-inclusive retrospective descriptive investigation. Demographics and clinical variables were recorded from adult patient health records (2002-2017) and analysed. Results: 21 Patients (17 females, 4 males) with median (IQR) age of 34 years (30.2-37.8) at HIV diagnosis and 45 years (39.5-47) at TLART initiation were included. Median duration (days) from HIV diagnosis to first-line ART initiation was 101 (37-367), treatment duration on first-line, second-line and between second-line failure and TLART initiation were: 1 269 (765-2 343); 1 512 (706-2096) and 71 (58-126) days respectively. | en_US |
| dc.identifier.citation | Viljoen, M. et al. (2020). A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa. African Health Sciences, 20(2), 549-559 | en_US |
| dc.identifier.issn | 1680-6905 | |
| dc.identifier.uri | 10.4314/ahs.v20i2.2 | |
| dc.identifier.uri | http://hdl.handle.net/10566/5603 | |
| dc.language.iso | en | en_US |
| dc.publisher | Makerere University | en_US |
| dc.subject | Drug resistance patterns | en_US |
| dc.subject | HIV | en_US |
| dc.subject | Salvage therapy | en_US |
| dc.subject | Third-line antiretroviral therapy | en_US |
| dc.subject | South Africa | en_US |
| dc.title | A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa | en_US |
| dc.type | Article | en_US |