A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa

dc.contributor.authorViljoen, Michelle
dc.contributor.authorRudman, Christian
dc.contributor.authorRheeders, Malie
dc.date.accessioned2021-01-07T11:05:57Z
dc.date.available2021-01-07T11:05:57Z
dc.date.issued2020
dc.description.abstractGreater access and prolonged exposure to ART may inevitably lead to more treatment failure and increase the need for third-line ART (TLART) in a resource-limited setting. Objective: To describe characteristics and resistance patterns of adult patients initiated on TLART in three districts of the North West province. Method: All-inclusive retrospective descriptive investigation. Demographics and clinical variables were recorded from adult patient health records (2002-2017) and analysed. Results: 21 Patients (17 females, 4 males) with median (IQR) age of 34 years (30.2-37.8) at HIV diagnosis and 45 years (39.5-47) at TLART initiation were included. Median duration (days) from HIV diagnosis to first-line ART initiation was 101 (37-367), treatment duration on first-line, second-line and between second-line failure and TLART initiation were: 1 269 (765-2 343); 1 512 (706-2096) and 71 (58-126) days respectively.en_US
dc.identifier.citationViljoen, M. et al. (2020). A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa. African Health Sciences, 20(2), 549-559en_US
dc.identifier.issn1680-6905
dc.identifier.uri10.4314/ahs.v20i2.2
dc.identifier.urihttp://hdl.handle.net/10566/5603
dc.language.isoenen_US
dc.publisherMakerere Universityen_US
dc.subjectDrug resistance patternsen_US
dc.subjectHIVen_US
dc.subjectSalvage therapyen_US
dc.subjectThird-line antiretroviral therapyen_US
dc.subjectSouth Africaen_US
dc.titleA retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africaen_US
dc.typeArticleen_US

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