Awareness of caregiver reporting of suspected adverse drug reactions in children treated for drug-resistant tuberculosis

dc.contributor.advisorKeuler, Nicole
dc.contributor.advisorOkeyo, Ida
dc.contributor.authorThomas, Duran
dc.date.accessioned2026-10-12T12:18:54Z
dc.date.available2026-10-12T12:18:54Z
dc.date.issued2026
dc.description.abstractIntroduction: Despite the advances in treatment for drug-resistant tuberculosis (DR-TB) in children, children are still at risk of developing adverse drug reactions (ADRs) during the prolonged treatment process. Monitoring and reporting of ADRs to ensure patient safety is a critical component of pharmacovigilance. The foundation of pharmacovigilance activities relies on ADR reporting by healthcare professionals and patients. However, there are limited studies that have focused on how caregivers of children navigate ADR reporting processes. This study aimed to explore the awareness of caregiver reporting of suspected ADRs in children treated for DR-TB. Methods: A qualitative exploratory study was conducted at Brooklyn Chest Hospital (BCH), a centralised provincial TB institution in Cape Town, between January and June 2025. The study consisted of two phases, phase one included direct observations of healthcare professionals (doctors, nurses, pharmacists) and caregivers for a period of two weeks (Monday to Friday). Phase two included semi-structured interviews with five caregivers
dc.identifier.urihttps://hdl.handle.net/10566/25548
dc.language.isoen
dc.publisherUniversity of the Western Cape
dc.subjectAwareness
dc.subjectCaregiver
dc.subjectReporting
dc.subjectAdverse drug reactions
dc.subjectChildren
dc.titleAwareness of caregiver reporting of suspected adverse drug reactions in children treated for drug-resistant tuberculosis
dc.typeThesis

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