DAMPD: a manually curated antimicrobial peptide database

Simple item page
dc.contributor.authorSundararajan, Vijayaraghava S.
dc.contributor.authorGabere, Musa N.
dc.contributor.authorPretorius, Ashley
dc.contributor.authorAdam, Saleem
dc.contributor.authorChristoffels, Alan
dc.contributor.authorMinna, Lehvaslaiho
dc.contributor.authorArcher, John A.C.
dc.contributor.authorBajic, Vladimir B.
dc.date.accessioned2015-06-22T13:38:24Z
dc.date.available2015-06-22T13:38:24Z
dc.date.issued2012
dc.description.abstractThe demand for antimicrobial peptides (AMPs) is rising because of the increased occurrence of pathogens that are tolerant or resistant to conventional antibiotics. Since naturally occurring AMPs could serve as templates for the development of new anti-infectious agents to which pathogens are not resistant, a resource that contains relevant information on AMP is of great interest. To that extent, we developed the Dragon Antimicrobial Peptide Database (DAMPD, http://apps.sanbi.ac.za/dampd) that contains 1232 manually curated AMPs. DAMPD is an update and a replacement of the ANTIMIC database. In DAMPD an integrated interface allows in a simple fashion querying based on taxonomy, species, AMP family, citation, keywords and a combination of search terms and fields (Advanced Search). A number of tools such as Blast, ClustalW, HMMER, Hydrocalculator, SignalP, AMP predictor, as well as a number of other resources that provide additional information about the results are also provided and integrated into DAMPD to augment biological analysis of AMPs.en_US
dc.description.accreditationWeb of Scienceen_US
dc.description.sponsorshipSouth African Research Chair Initiative National Research Foundation of South Africa Base Chair Research Funds of V.B.B.en_US
dc.identifier.citationSundararajan, Vijayaraghava, S. et al. (2011). DAMPD: a manually curated antimicrobial peptide database. Nucleic Acids Research, 40(D1): D1108-D1112
dc.identifier.issn0305-1048
dc.identifier.urihttp://hdl.handle.net/10566/1522
dc.language.isoenen_US
dc.privacy.showsubmitterfalse
dc.publisherOxford University Pressen_US
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.source.urihttp://dx.doi.org/10.1093/nar/gkr1063
dc.status.ispeerreviewedtrue
dc.subjectDragon Antimicrobial Peptide Database (DAMPD)
dc.subjectAntimicrobial peptides (AMPs)
dc.titleDAMPD: a manually curated antimicrobial peptide databaseen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
sundararajan_dampd_nucleic_2012.pdf
Size:
88.2 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.55 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Research Articles (SANBI)
Prof. Alan Christoffels