Fractions of Hoslundia opposita Vahl and hoslundin induced apoptosis in human cancer cells via mitochondrial-dependent reactive oxygen species (ROS) generation

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dc.contributor.authorAjibare, Abosede Christiana
dc.contributor.authorEbuehi, Osaretin Albert Taiwo
dc.contributor.authorAkinyede, Kolajo Adedamola
dc.date.accessioned2022-08-30T08:44:34Z
dc.date.available2022-08-30T08:44:34Z
dc.date.issued2022
dc.description.abstractancer remains one of the leading causalities of several morbidity and mortality with negative impact on global economy due to low workforce and management/treatment cost. A number of conventional therapies have been explored in the management/treatment of cancer including chemotherapeutic intervention, radiotherapy, and surgery. Among these treatment modalities, chemotherapy remains the most popular first line of intervention in management/treatment of cancer, and natural products have been implicated as the main source of antineoplastic agents with phenomenal efficacy. However, current antineoplastic agents suffer from lack of selectivity and specificity necessitating the need for further research in the search for novel anticancer drug molecules.en_US
dc.identifier.citationAjibare, A. C. et al. (2022). Fractions of Hoslundia opposita Vahl and hoslundin induced apoptosis in human cancer cells via mitochondrial-dependent reactive oxygen species (ROS) generation. Biomedicine and Pharmacotherapy, 153, 113475. https://doi.org/10.1016/j.biopha.2022.113475en_US
dc.identifier.issn0753-3322
dc.identifier.urihttps://doi.org/10.1016/j.biopha.2022.113475
dc.identifier.urihttp://hdl.handle.net/10566/7779
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectCanceren_US
dc.subjectTumourigenicen_US
dc.subjectHoslundinen_US
dc.subjectNatural productsen_US
dc.subjectChemotherapyen_US
dc.titleFractions of Hoslundia opposita Vahl and hoslundin induced apoptosis in human cancer cells via mitochondrial-dependent reactive oxygen species (ROS) generationen_US
dc.typeArticleen_US

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