An evaluation of the biopesticidal characteristics of Helichrysum marifolium and Helichrysum patulum and their effects on animal metabolism

dc.contributor.advisorWeitz, Frans
dc.contributor.authorSpeelman, Abigail
dc.date.accessioned2022-11-15T08:53:35Z
dc.date.accessioned2024-11-04T13:15:32Z
dc.date.available2022-11-15T08:53:35Z
dc.date.available2024-11-04T13:15:32Z
dc.date.issued2002
dc.descriptionMagister Scientiae (Medical Bioscience) - MSc(MBS)en_US
dc.description.abstractThere ate a number of pesticides that are suspected to be endocrine disrupters' Many of these pesticides are man-made. Endocrine disrupters are chemicals that can lead to an increase in birth defects, sexual abnormalities, and reproductive failure. Marine animals seem to be the most vulnerable to the effects of pesticides since the ocean is the final sink for many pollutants. Endocrine disrupters can exert their effects in many ways. They can either bind to the hormone's receptor and mimic the hormone, or block the action of the hormone' An experiment done of newborn female rats injected with 1mg DDT/day on days 2-4 after birth had early onset of puberty and accelerated loss of fertility. ln another experiment, vinclozolin (also a pesticide) at dosage levels of 3mg/kg/day resulted in feminised male rats in the womb and an abnormal number of nipples were observed (11). Pesticides can be absorbed through the skin, by inhalation or oral ingestion. There are, however, important quantitative differences between the various derivatives. The skin poorly absorbs DDT in solution, whereas dieldrin absorption by the skin is very efficient. The major effects of insecticides in humans are qualitatively similar and cause effects on the central nervous system (9).en_US
dc.identifier.urihttps://hdl.handle.net/10566/17306
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectHelichrysum marifoliumen_US
dc.subjectHelichrysum patulumen_US
dc.subjectBotrytis cinereaen_US
dc.subjectVenturia inaequalisen_US
dc.subjectAntifungalen_US
dc.subjectBiopesticidesen_US
dc.subjectConventional pesticidesen_US
dc.subjectAtomic Absorption Spectrophotometry (AA)en_US
dc.subjectUV/Visible Spectrophotometryen_US
dc.subjectAnimal metabolism, haematology and tissue histologyen_US
dc.titleAn evaluation of the biopesticidal characteristics of Helichrysum marifolium and Helichrysum patulum and their effects on animal metabolismen_US

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