Advancement in electrochemical sensing of chloramphenicol in varying matrixes: a review

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dc.contributor.authorMulaudji, Kgwadu Percy
dc.contributor.authorMokwebo, Kefilwe Vanessa
dc.contributor.authorDe Bruin, Franklin Quelain
dc.contributor.authorPokpas, Keagan
dc.contributor.authorRoss, Natasha
dc.date.accessioned2025-11-27T09:58:44Z
dc.date.available2025-11-27T09:58:44Z
dc.date.issued2025
dc.description.abstractChloramphenicol (CAP) have demonstrated its broad effectiveness against bacterial infections. However, its persistence in the environment and potential toxicity led to strict global regulations limiting its use. As a result, rapid and accurate detection methods for CAP are being developed to protect public health and maintain regulatory compliance regarding its presence in the environment. Conventional analytical methods such as High-Performance Liquid Chromatography, Gas Chromatography, and Liquid Chromatography–Mass Spectrometry were commonly used for CAP detection. However, these conventional methods suffer challenges such as time-consumption, fabrication complexity, reproducibility, and cost. With electrochemical sensing techniques presenting varying valuable benefits, such as instant detection, low power consumption, simultaneous analysis, and portability, making them essential for timely monitoring of various analytes. The performance of electrochemical sensor is further boosted by integrating materials such as spinels, metal oxides, and metallic nanoparticles. These materials are broadly investigated as electrode interface components thanks to their features that collectively boost electrochemical sensor such as providing excellent electrical conductivity, distinct catalytic behavior, and larger surface areas. Furthermore, this paper reviews the impact of traditional and standards analytical methods, as well as their recent advancement based on the detection of CAP in aqueous media.
dc.identifier.citationMulaudji, K.P., Mokwebo, K.V., De Bruin, F.Q., Pokpas, K. and Ross, N., 2025. Advancement in electrochemical sensing of Chloramphenicol in varying matrixes: A review. Talanta Open, p.100561.
dc.identifier.issnhttps://doi.org/10.1016/j.talo.2025.100561
dc.identifier.urihttps://doi.org/10.1177/27536130251349456
dc.identifier.urihttps://hdl.handle.net/10566/21482
dc.language.isoen
dc.publisherElsevier B.V.
dc.subjectChloramphenicol
dc.subjectElectrochemical sensing
dc.subjectNanomaterials
dc.subjectPublic health
dc.subjectToxicity
dc.titleAdvancement in electrochemical sensing of chloramphenicol in varying matrixes: a review
dc.typeArticle

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