A case report on an ulcerative peripheral giant cell granuloma

Abstract

Peripheral Giant Cell Granuloma (PGCG) is a localized non-neoplastic lesion, characterized by reactive hyperplasia associated with plaque and calculus build up and any other local irritation and can also associated with oral trauma. PGCG has a purplish to reddish appearance, presenting as a soft to firm exophytic growth with a pedicle or sessile base, and has a smooth surface which can be ulcerated. Histological analysis of PCGC demonstrated a polypoidal biopsy comprising squamous mucosa with ulceration. Within the stroma, there was an unencapsulated proliferation comprising numerous osteoclast-type giant cells embedded within a fibrous stroma with extravasation of red blood cells. This case report s on a PGCG diagnosed in the maxilla of an adult, female patient managed by surgical excision which had no recurrence.