Synthesis, characterization, and molecular docking of novel 4-Aminoquinolines and Salicylaldimine complexes: evaluation as antimalarial and antitumor agents

dc.contributor.advisor	Onani, Martin O.
dc.contributor.author	Busa, Asanda V.
dc.date.accessioned	2018-02-14T09:24:58Z
dc.date.accessioned	2024-05-13T12:40:40Z
dc.date.available	2018-04-30T22:10:06Z
dc.date.available	2024-05-13T12:40:40Z
dc.date.issued	2016
dc.description	Philosophiae Doctor - PhD (Chemistry)
dc.description.abstract	Malaria remains a major global health problem and to date, hundreds of thousands of people die as a result of this disease every year. Malaria has been able to adapt and rebound despite various efforts made to combat the disease. The decrease in efficacy of many front-line drugs against malaria, due to increased resistance, prompts investigation into obtaining effective compounds that are able to overcome this resistance. This study investigated the synthesis, characterisation and biological evaluation of new quinoline (as antimalarial agents) as well as non-quinoline (as antitumor agents) based compounds.
dc.identifier.uri	https://hdl.handle.net/10566/14719
dc.language.iso	en
dc.publisher	University of the Western Cape
dc.rights.holder	University of the Western Cape
dc.title	Synthesis, characterization, and molecular docking of novel 4-Aminoquinolines and Salicylaldimine complexes: evaluation as antimalarial and antitumor agents

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