Synthesis and characterisation of biomimetic immunostimulatory lipid-polymer hybrid nanoparticles

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dc.contributor.advisorDube, Admire
dc.contributor.authorIrabin, Aime Fabius
dc.date.accessioned2023-02-13T07:16:23Z
dc.date.accessioned2024-10-29T13:17:58Z
dc.date.available2023-02-13T07:16:23Z
dc.date.available2024-10-29T13:17:58Z
dc.date.issued2022
dc.description>Magister Scientiae - MScen_US
dc.description.abstractTuberculosis (TB), caused by Mycobacterium tuberculosis (M. tuberculosis), remains a fatal infectious disease and one of the top ten leading causes of mortality, particularly in developing countries. Current drug therapy for TB is challenged by the poor physiochemical properties of the antibiotics used. These properties impact their bioavailability, toxicity, and treatment duration, thereby negatively impacting patient adherence. These factors also contribute to the emergence of the difficult to treat multi-drug resistant strains of M. tuberculosis. Recently, immunotherapy has emerged as a promising alternative treatment modality for TB.en_US
dc.identifier.urihttps://hdl.handle.net/10566/16346
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectNanoparticlesen_US
dc.subjectImmunotherapyen_US
dc.subjectTuberculosisen_US
dc.subjectPharmacologyen_US
dc.subjectNanomedicineen_US
dc.titleSynthesis and characterisation of biomimetic immunostimulatory lipid-polymer hybrid nanoparticlesen_US

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