Fabrication of luminescent nanocomposites for diagnosis of breast cancer
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Date
2016
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Publisher
University of the Western Cape
Abstract
In this study we were able to synthesize separately iron oxide magnetic nanoparticles, InP/ZnSe
and CdTe/ZnS quantum dots. The iron oxide nanoparticles were coupled with InP/ZnSe QDs to
form the luminescent magnetic nanocomposite. The magnetic nanoparticles of the type iron
oxide (?-Fe2O3) were synthesized using co-precipitation method owing to its advantages. The
fluorescing material InP/ZnSe quantum dots were synthesized using hot injection technique.
Meso-2,3-dimercaptosuccinic acid, 3-mercaptopropionic acid, and L-cysteine were used to
functionalize the iron oxide nanoparticles. The synthesized InP/ZnSe quantum dots were made
water soluble by carrying out ligand exchange processes. The synthesized magnetic
nanoparticles were characterized using high-resolution transmission electron microscopy
(HRTEM), X-ray diffractometer (XRD), Fourier transform infra-red spectroscopy (FTIR) and
superconducting quantum interference device (SQUID). The quantum dots were characterized
using photoluminescence Nanolog (PL), HRTEM, XRD, and FTIR. The fluorescent
nanocomposite (?-Fe2O3-InP/ZnSe) was characterized using PL, SQUID, and HRTEM.
Description
Philosophiae Doctor - PhD (Chemistry)