Synthesis, physicochemical characterization, toxicity and efficacy of a PEG conjugate and a hybrid PEG conjugate nanoparticle formulation of the antibiotic moxifloxacin

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dc.contributor.authorDube, Admire
dc.contributor.authorTshweu, Lesego L.
dc.contributor.authorShemis, Mohamed Abbas
dc.date.accessioned2020-12-15T07:39:07Z
dc.date.available2020-12-15T07:39:07Z
dc.date.issued2020
dc.description.abstractAntibiotic resistance is increasing at such an alarming rate that it is now one of the greatest global health challenges. Undesirable toxic side-effects of the drugs lead to high rates of non-completion of treatment regimens which in turn leads to the development of drug resistance. We report on the development of delivery systems that enable antibiotics to be toxic against bacterial cells while sparing human cells.en_US
dc.identifier.citation17. Dube, A. et al. (2020). Synthesis, physicochemical characterization, toxicity and efficacy of a PEG conjugate and a hybrid PEG conjugate nanoparticle formulation of the antibiotic moxifloxacin. RSC Advances,10(34),19770-19780en_US
dc.identifier.issn2046-2069
dc.identifier.uri10.1039/c9ra10872f
dc.identifier.urihttp://hdl.handle.net/10566/5512
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.subjectPEG conjugateen_US
dc.subjectHybrid PEG conjugateen_US
dc.subjectAntibioticen_US
dc.subjectDrugsen_US
dc.subjectMoxifloxacinen_US
dc.titleSynthesis, physicochemical characterization, toxicity and efficacy of a PEG conjugate and a hybrid PEG conjugate nanoparticle formulation of the antibiotic moxifloxacinen_US
dc.typeArticleen_US

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