Genetic lesions within the 3a gene of SARS-CoV

Abstract

A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained from SARS-CoV infected patients also contains a heterogeneous population of wild-type and mutant 3a transcripts.

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Citation

Tan, T., et al. (2005). Genetic lesions within the 3a gene of SARS-CoV. Virology Journal, 2: 51