Evaluation of the effects of Olea europaea L. subsp. africana (Mill.) P.S. Green (Oleaceae) leaf methanol extract against castor oil-induced diarrhoea in mice

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dc.contributor.authorAmabeoku, George J.
dc.contributor.authorBamuamba, Kapinga
dc.date.accessioned2023-03-07T08:58:23Z
dc.date.available2023-03-07T08:58:23Z
dc.date.issued2010
dc.description.abstractOlea europaea L. subsp. africana (Mill.) P.S. Green is widely used in South Africa by traditional medicine practitioners to treat diarrhoea. However, little is known scientifically about this South African species in the treatment of diarrhoea. The main aim of the study therefore was to investigate the antidiarrhoeal effect of the leaf methanol extract of the plant species in mice. The antidiarrhoeal activity of the leaf methanol extract of O. europaea subsp. africana was studied using a castor oil-induced diarrhoeal test. The antipropulsive activity of the plant extract was also investigated using the charcoal meal transit test. Standard methods were used to investigate the acute toxicity and effect of O. europaea subsp. africana on castor oil-induced intraluminal fluid accumulation.en_US
dc.identifier.citationAmabeoku, G. J., & Bamuamba, K. (2010). Evaluation of the effects of Olea europaea L. subsp. africana (Mill.) P.S. Green (Oleaceae) leaf methanol extract against castor oil-induced diarrhoea in mice. Journal of Pharmacy and Pharmacology, 62 (3) ,368-373. https://doi.org/10.1211/jpp.62.03.0012en_US
dc.identifier.issn2042-7158
dc.identifier.urihttps://doi.org/10.1211/jpp.62.03.0012
dc.identifier.urihttp://hdl.handle.net/10566/8543
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.subjectAcute toxicityen_US
dc.subjectAntidiarrhoealen_US
dc.subjectOleaceaeen_US
dc.subjectPharmacologyen_US
dc.subjectDiarrhoeaen_US
dc.titleEvaluation of the effects of Olea europaea L. subsp. africana (Mill.) P.S. Green (Oleaceae) leaf methanol extract against castor oil-induced diarrhoea in miceen_US
dc.typeArticleen_US

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