Meldola’s Blue immobilised onto mesoporous carbon aerogel surface as non-enzymatic electrode matrix for sensitive hydrogen peroxide determination

Abstract

Meldola Blue (MB) immobilised on mesoporous carbon aerogel (CA) (i.e., MBCA) in chitosan (Chi) solution was used as a modifying matrix at a glassy carbon electrode (GCE) and applied for electrochemical detection of H2O2 in a pharmaceutical product. The obtained MBCA composite was morpho-structurally investigated by XRD and N2 adsorption-desorption measurements. Cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and amperometry were used to estimate the electrochemical (scan rate, pH, etc.) and analytical parameters of H2O2 electro-reduction at the MBCA-Chi/GCE modified electrode. The high sensitivity (1.72 A/M), wide linear range (0.25 – 2.5 μM), and low detection limit (48.8 nM) highlight the importance of the high specific surface area provided by CA, which, when combined with MB, results in an increased electrode active surface area and enhanced H2O2 detection performance. The new developed modified electrode was tested for the electroanalytical detection of H2O2 in synthetic and real samples.