Synthesis and cytotoxic evaluation of gum arabic surface modified cadmium telluride quantum dots
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Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
American Scientific Publishers
Abstract
Water-soluble cadmium telluride (CdTe) quantum dots (QDs) were capped with gum Arabic (GA) is a non-toxic,
water-soluble glycoprotein polymer commonly used in the food and pharmaceutical industries. The GA was
used to stabilise cadmium telluride quantum dots (GA-QDs) and provides functional groups for other molecules
such as nucleic acids, peptides and antibodies to be attached to the QDs for biological and biomedical applications.
In this study, the GA was used to cap and stabilise QDs using two different methods. These QDs
were characterised using Ultraviolet-visible (UV-vis) and Photoluminescence (PL) spectroscopy, X-powder ray
diffraction (XRD), High-resolution transmission electron microscopy, zeta potential and particle size distributions.
Cytotoxicity of these QDs was also investigated using four different human cell lines; HeLa, MCF-7, PC-3
and U87 cancer cells.
Description
Keywords
Quantum dots (QD), Gum arabic (GA), Cadmium telluride (CdTe), Cancer cells, Cytotoxicity
Citation
Edwina, U. O. et al. (2020). Synthesis and cytotoxic evaluation of gum arabic surface modified cadmium telluride quantum dots. An International Journal on Multidisciplinary Materials Research, 10,(5,) :611- 769