Long-term exposure to outdoor and household air pollution and blood pressure in the prospective urban and rural epidemiological (pure) study

dc.contributor.authorPuoane, Thandi
dc.contributor.authorArku, Raphael E.
dc.contributor.authorBrauer, Michael
dc.date.accessioned2021-01-25T12:55:50Z
dc.date.available2021-01-25T12:55:50Z
dc.date.issued2020
dc.description.abstractExposure to air pollution has been linked to elevated blood pressure (BP) and hypertension, but most research has focused on short-term (hours, days, or months) exposures at relatively low concentrations. We examined the associations between long-term (3-year average) concentrations of outdoor PM2.5 and household air pollution (HAP) from cooking with solid fuels with BP and hypertension in the Prospective Urban and Rural Epidemiology (PURE) study. Outdoor PM2.5 exposures were estimated at year of enrollment for 137,809 adults aged 35–70 years from 640 urban and rural communities in 21 countries using satellite and ground-based methods. Primary use of solid fuel for cooking was used as an indicator of HAP exposure, with analyses restricted to rural participants (n = 43,313) in 27 study centers in 10 countries. BP was measured following a standardized procedure and associations with air pollution examined with mixed-effect regression models, after adjustment for a comprehensive set of potential confounding factors. Baseline outdoor PM2.5 exposure ranged from 3 to 97 μg/m3 across study communities and was associated with an increased odds ratio (OR) of 1.04 (95% CI: 1.01, 1.07) for hypertension, per 10 μg/m3 increase in concentration.en_US
dc.identifier.citationPuoane, T. et al. (2020). Long-term exposure to outdoor and household air pollution and blood pressure in the prospective urban and rural epidemiological (pure) study. Environmental Pollution, 262,114197en_US
dc.identifier.issn1873-6424
dc.identifier.uri10.1016/j.envpol.2020.114197
dc.identifier.urihttp://hdl.handle.net/10566/5753
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectAir pollutionen_US
dc.subjectBlood pressureen_US
dc.subjectCardiovascularen_US
dc.subjectGlobal healthen_US
dc.subjectHouseholden_US
dc.titleLong-term exposure to outdoor and household air pollution and blood pressure in the prospective urban and rural epidemiological (pure) studyen_US
dc.typeArticleen_US

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