Application of consolidated framework for implementation research to improve Clostridioides difficile infection management in district hospitals

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Date

2022

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

Clostridioides difficile infection (CDI) contributes the global threats of drug resistant infections, healthcare acquired infections and antimicrobial resistance. Yet CDI knowledge among healthcare providers in low-resource settings is limited and CDI testing, treatment, and infection prevention measures are often delayed. To develop a CDI intervention informed by the local context within South African public district level hospitals, and analyze the CDI intervention and implementation process. A CDI checklist intervention was designed and implemented at three district level hospitals in the Western Cape, South Africa that volunteered to participate. Data collection included a retrospective medical records review of patients hospitalized with C. difficile test orders during the 90 days post-implementation. Patient outcomes and checklist components (e.g. antibiotics) were collected.

Description

Keywords

Public health, Global health, South Africa, Implementation science, Clostridioides difficile infection

Citation

Legenza, L. et al. (2023). Application of consolidated framework for implementation research to improve Clostridioides difficile infection management in district hospitals. Research in Social and Administrative Pharmacy, 18(12), 4100-4111. https://doi.org/10.1016/j.sapharm.2022.07.046