Adverse pregnancy outcomes among HIV-positive pregnant women treated with efavirenz-containing antiretroviral drugs: a retrospective cohort study in the Cape Flats

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dc.contributor.advisorMugabo, Pierre
dc.contributor.authorMohammednur, Mohammedmekin Mohammedseid
dc.date.accessioned2018-08-02T12:27:41Z
dc.date.accessioned2024-05-15T07:16:51Z
dc.date.available2018-08-02T12:27:41Z
dc.date.available2024-05-15T07:16:51Z
dc.date.issued2017
dc.descriptionDoctor Pharmaceuticae - Dpharmen_US
dc.description.abstractThe use of efavirenz (EFV) in the first trimester of pregnancy remains controversial. In South Africa, the use of EFV-containing antiretroviral therapy (ART) as part of a Fixed Dose Combination (FDC) during the first trimester of pregnancy started in April, 2013. Literature to date has reported conflicting outcomes following the use of EFV-containing ART during the first trimester of pregnancy. The objectives of the study were to determine the prevalence of adverse pregnancy outcomes among HIV-positive pregnant women treated with EFV-containing ART and compare these results with those of pregnant women treated with NVP-containing ART and HIV-negative pregnant women in resource-limited settings. In addition, the study also aimed to determine the effect of the time of initiation of ART on the prevalence of adverse pregnancy outcomes.en_US
dc.identifier.urihttps://hdl.handle.net/10566/15058
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectAdverse pregnancy outcomesen_US
dc.subjectAntiretroviral drugen_US
dc.subjectBirth defecten_US
dc.subjectEfavirenzen_US
dc.subjectFirst trimesteren_US
dc.subjectHIVen_US
dc.subjectLow birth weighten_US
dc.subjectNevirapineen_US
dc.subjectPregnant womenen_US
dc.subjectPreterm deliveryen_US
dc.titleAdverse pregnancy outcomes among HIV-positive pregnant women treated with efavirenz-containing antiretroviral drugs: a retrospective cohort study in the Cape Flatsen_US
dc.typeThesisen_US

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