Quantum dots for multiplexed biological imaging
| dc.contributor.advisor | Onani, M.O | |
| dc.contributor.author | Mtotywa, Alungile | |
| dc.date.accessioned | 2023-07-19T08:25:09Z | |
| dc.date.accessioned | 2024-05-13T12:40:25Z | |
| dc.date.available | 2023-07-19T08:25:09Z | |
| dc.date.available | 2024-05-13T12:40:25Z | |
| dc.date.issued | 2023 | |
| dc.description | >Magister Scientiae - MSc | en_US |
| dc.description.abstract | Over the past two decades, indium phosphide (InP) colloidal quantum dots (QDs) have attracted substantial interest as a possibly less hazardous alternative to cadmium-based QDs. The improvements in their colloidal synthesis techniques have made it possible to synthesize a wide range of compositions, and ligands with perfect quantum yields close to unity, spectrum tunability from blue to near-infrared, and narrow emission linewidths. Additionally, InP QDs have better optical stability than cadmium chalcogenides due to their higher covalency. Modern InP QDs have demonstrated superior performance in a wide range of applications, including solar cells with strong commercial potential, luminescent solar concentrators (LSCs), and light-emitting diodes. The use of non-cadmium-based quantum dots (QDs) as highly effective, non-toxic optical probes for bioimaging is discussed in this study. Core/ shell InP/ZnS and InP/ZnSe QDs were synthesized using tris (dialkylamino) phosphines via one-pot synthesis. Water compatibility was achieved through ligand exchange with 3- mercaptopropionic acid. Chitosan was further added to make the QDs more stable and less toxic. All the synthesized QDs were characterized with UV-Vis, PL, FTIR, and HRTEM. | en_US |
| dc.identifier.uri | https://hdl.handle.net/10566/14680 | |
| dc.language.iso | en | en_US |
| dc.publisher | University of the Western Cape | en_US |
| dc.rights.holder | University of the Western Cape | en_US |
| dc.subject | Quantum dots | en_US |
| dc.subject | Indium Phosphide | en_US |
| dc.subject | Bioimaging | en_US |
| dc.subject | Cytotoxicity | en_US |
| dc.title | Quantum dots for multiplexed biological imaging | en_US |