Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City

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Date

2021

Journal Title

Journal ISSN

Volume Title

Publisher

Public Library of Science

Abstract

During the first phase of the COVID-19 epidemic, New York City rapidly became the epicenter of the pandemic in the United States. While molecular phylogenetic analyses have previously highlighted multiple introductions and a period of cryptic community transmission within New York City, little is known about the circulation of SARS-CoV-2 within and among its boroughs. We here perform phylogeographic investigations to gain insights into the circulation of viral lineages during the first months of the New York City outbreak. Our analyses describe the dispersal dynamics of viral lineages at the state and city levels, illustrating that peripheral samples likely correspond to distinct dispersal events originating from the main metropolitan city areas. In line with the high prevalence recorded in this area, our results highlight the relatively important role of the borough of Queens as a transmission hub associated with higher local circulation and dispersal of viral lineages toward the surrounding boroughs.

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Keywords

Covid-19, New York City, SARS-CoV-2, Public health, Sustainable Development Goals

Citation

Dellicour, S. et al. (2021). Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City. PLoS Pathogens, 17(5), e1009571. 10.1371/journal.ppat.1009571