Wound healing activities and potential of selected african medicinal plants and their synthesized biogenic nanoparticles
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Date
2021-11
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Abstract
In Africa, medicinal plants have been traditionally used as a source of medicine for
centuries. To date, African medicinal plants continue to play a significant role in the treatment of
wounds. Chronic wounds are associated with severe healthcare and socio-economic burdens despite
the use of conventional therapies. Emergence of novel wound healing strategies using medicinal
plants in conjunction with nanotechnology has the potential to develop efficacious wound healing
therapeutics with enhanced wound repair mechanisms. This review identified African medicinal
plants and biogenic nanoparticles used to promote wound healing through various mechanisms
including improved wound contraction and epithelialization as well as antibacterial, antioxidant
and anti-inflammatory activities. To achieve this, electronic databases such as PubMed, Scifinder®
and Google Scholar were used to search for medicinal plants used by the African populace that
were scientifically evaluated for their wound healing activities in both in vitro and in vivo models
from 2004 to 2021. Additionally, data on the wound healing mechanisms of biogenic nanoparticles
synthesized using African medicinal plants is included herein. The continued scientific evaluation of
wound healing African medicinal plants and the development of novel nanomaterials using these
plants is imperative in a bid to alleviate the detrimental effects of chronic wounds.
Description
Keywords
African medicinal plants, Biogenic nanoparticles, Wound healing, Antibacterial
Citation
Tyavambiza, C.; Dube, P.; Goboza, M.; Meyer, S.; Madiehe, A.M.; Meyer, M. Wound Healing Activities and Potential of Selected African Medicinal Plants and Their Synthesized Biogenic Nanoparticles. Plants 2021, 10, 2635. https:// doi.org/10.3390/plants10122635