Metallic nanoparticles with polymeric shell: A multifunctional platform for application to biosensor
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Date
2018
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
University of the Western Cape
Abstract
Tuberculosis (TB) is an airborne disease caused by Mycobacterium tuberculosis (MTB) that
usually affects the lungs leading to severe coughing, fever and chest pains. It was estimated
that over 9.6 million people worldwide developed TB and 1.5 million died from the infectious
disease of which 12 % were co-infected with human immunodeficiency virus (HIV) in the year
2015. In 2016 the statistics increased to a total of 1.7 million people reportedly died from TB
with an estimated 10.4 million new cases of TB diagnosed worldwide. The development of the
efficient point-of-care systems that are ultra-sensitive, cheap and readily available is essential
in order to address and control the spread of the tuberculosis (TB) disease and multidrugresistant
tuberculosis.
Description
Philosophiae Doctor - PhD (Chemistry)
Keywords
Cytochrome P450-2E1, Differential Pulse Voltammetry, Enzyme-linked immunosorbent assay, Ethambutol, First-line anti-TB drugs, Glassy carbon electrode, Immunosensor, Multidrug-resistance, Mycobacterium tuberculosis Ag85B, Polyamic acid, Polypyrrole, Rifampicin, Silver nanoparticles, Square wave voltammetry, Tuberculosi,