Enhanced anti-bacterial activity of biogenic silver nanoparticles synthesized from terminalia mantaly extracts
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Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
Dove Press
Abstract
The global increase in outbreaks and mortality rates associated with multidrug-
resistant (MDR) bacteria is a major health concern and calls for alternative treatments.
Natural-derived products have shown potential in combating the most dreadful diseases, and
therefore serve as an effective source of bioactive compounds that can be used as antibacterial
agents. These compounds are able to reduce metal ions and cap nanoparticles to
form biogenic nanoparticles (NPs) with remarkable anti-bacterial activities. This study
explores the use of Terminalia mantaly (TM) extracts for the synthesis of biogenic silver
NPs (TM-AgNPs) and the evaluation of their antibacterial activity. TM-AgNPs were synthetized by the reduction of AgNO3 with aqueous andmethanolic
TM extracts. UV–visible (UV-vis) spectrophotometry, Dynamic Light Scattering (DLS),
Transmission Electron Microscopy, and Fourier Transform Infrared (FTIR) analyses were used
to characterise the TM-AgNPs. Anti-bacterial activity of the TM extracts and TM-AgNPs was
evaluated against eight bacterial strains using the broth microdilution assay.
Description
Keywords
Biotechnology, Nanotechnology, Green synthesis, Antibacterial activity, Statistics studies, Population studies
Citation
Majoumouo, M. S. et al. (2019). Enhanced anti-bacterial activity of biogenic silver nanoparticles synthesized from terminalia mantaly extracts. International Journal Of Nanomedicine, 14 , 9031-9046. 10.2147/IJN.S223447