An efficient inclusion complex based fluorescent sensor for mercury (ii) and its application in live cell imaging
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Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Springer
Abstract
The formation of an inclusion complex between hydroxypropyl-β-cyclodextrin (H-CD) and 4-acetylphenyl-4-(((6-
chlorobenzo[d]thiazol-2-yl)-imino)-methyl)-benzoate (L) was investigated by FT-IR, 1
H-NMR, X-ray difraction (XRD),
FT-Raman, scanning electron microscope (SEM) techniques in the solid-state, absorption and emission spectroscopy in the
liquid state and the virtual state as molecular docking technique. The binding properties of the inclusion complex (H-CD:
L) with cations in deionized water was observed via absorbance and photoluminescence (PL) emission spectroscopy. The
fuorescence probe (H-CD: L) inclusion complex (IC) was examined for several heavy metal cations, and identifed that the
PL emission wavelength of the complex displayed a continuous rise in the fuorescence intensity for Hg2+. A linearity range
of 1× 10–8 – 11× 10–8 M and limit of detection value of 2.71×10–10 M was found to be achieved for the detection of Hg2+.
This outcome proves that the inclusion complex H-CD: L would be a promising material for the development a solid-state
fuorescence probe for detecting Hg2+. It also shows application in real sample analysis and cell imaging.
Description
Keywords
Colorimetric, Fluorescence, Chemosensor, Methylene blue
Citation
Keerthana, P. et al. (2022). An efficient inclusion complex based fluorescent sensor for mercury (ii) and its application in live cell imaging. Journal of Fluorescence, 32(3), 1109-1124. 10.1007/s10895-022-02931-4