The role of surface modified TiO2 nanoparticles for application in 68Ge/68Ga generator systems and the use of molecular imprinted polymers for 68Ge breakthrough control

dc.contributor.advisorPetrik, Leslie
dc.contributor.authorBuwa, Sizwe
dc.date.accessioned2022-03-22T12:05:20Z
dc.date.accessioned2024-05-09T10:51:24Z
dc.date.available2024-05-09T10:51:24Z
dc.date.issued2021
dc.description>Magister Scientiae - MScen_US
dc.description.abstractTitanium dioxide (TiO2) has potential as an adsorbent within the 68Ge/68Ga generator context. To function effectively, three basic requirements are required: optimum 68Ga elution efficiency, stability and removal of the 68Ge breakthrough. After analysis of the 68Ga elution efficiency and the 68Ge breakthrough, two models are proposed, namely; surface modification and molecular imprinted polymer, to address factors influencing 68Ga elution efficiency and minimize 68Ge breakthrough. The surface modifiers that were investigated are 3-aminopolypropyltriethoxy silane (3-APTES), 3-mercaptopropyltrimethoxy silane (3-MPTMS), bis(3-aminopropyl)amine (BAPA) and 2-chloro-4,6-dimethoxy-1,3,5-triazine silane (CDMT).en_US
dc.description.embargo2023
dc.identifier.urihttps://hdl.handle.net/10566/14601
dc.language.isoenen_US
dc.publisherUniversity of Western Capeen_US
dc.rights.holderUniversity of Western Capeen_US
dc.subject68Ga efficiencyen_US
dc.subject68Ga elutionen_US
dc.subject68Ga radionuclideen_US
dc.subjectAdsorption hysteresisen_US
dc.subjectAdsorption isothermen_US
dc.titleThe role of surface modified TiO2 nanoparticles for application in 68Ge/68Ga generator systems and the use of molecular imprinted polymers for 68Ge breakthrough controlen_US

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