The practicality of the use of liquid biopsy in early diagnosis and treatment monitoring of oral cancer in resource- limited settings

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dc.contributor.authorAdeola, Henry Ademola
dc.contributor.authorBello, Ibrahim O.
dc.contributor.authorAruleba, Raphael Taiwo
dc.date.accessioned2022-09-19T09:42:49Z
dc.date.available2022-09-19T09:42:49Z
dc.date.issued2022
dc.description.abstractAn important driving force for precision and individualized medicine is the provision of tailor-made care for patients on an individual basis, in accordance with best evidence practice. Liquid biopsy(LB) has emerged as a critical tool for the early diagnosis of cancer and for treatment monitoring, but its clinical utility for oral squamous cell carcinoma (OSCC) requires more research and validation. Hence, in this review, we have discussed the current applications of LB and the practicality of its routine use in Africa; the potential advantages of LB over the conventional “gold-standard” of tissue biopsy; and finally, practical considerations were discussed in three parts: pre-analytic, analytic processing, and the statistical quality and postprocessing phases.en_US
dc.identifier.citationAdeola, .H. A. et al. (2022). The practicality of the use of liquid biopsy in early diagnosis and treatment monitoring of oral cancer in resource- limited settings. Cancers, 14(5),1139. https://doi.org/10.3390/cancers14051139en_US
dc.identifier.issn2072-6694
dc.identifier.urihttps://doi.org/10.3390/cancers14051139
dc.identifier.urihttp://hdl.handle.net/10566/7911
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.subjectOral Canceren_US
dc.subjectLiquid biopsyen_US
dc.subjectTumour cellsen_US
dc.subjectOral squamous cell carcinomaen_US
dc.subjectAfricaen_US
dc.titleThe practicality of the use of liquid biopsy in early diagnosis and treatment monitoring of oral cancer in resource- limited settingsen_US
dc.typeArticleen_US

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