The antimicrobial activity of biogenic silver nanoparticles synthesized from extracts of Red and Green European pear cultivars
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Date
2021-01
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Publisher
Taylor & Francis
Abstract
Green nanotechnology stands amongst the leading giants of innovation for the twenty first century
technological advances. More interesting, is the use of natural products as reducing agents. These
could be recyclable materials from fruits and vegetables to produce nanoparticles (NPs) with novel
properties. In the current study, silver NPs (AgNPs) were synthesized using the water extracts from the
peel and flesh of two Pyrus communis L. cultivars, namely, the Forelle (Red) Pears (RPE) and Packham
Triumph (Green) Pears (GPE). The AgNPs were characterized by UV-Vis spectrophotometry, Dynamic
Light Scattering (DLS), High Resolution Transmission Electron Microscopy (HRTEM) and Fourier
Transform Infra-Red Spectroscopy (FTIR). The antibacterial activities of the AgNPs were evaluated using
agar well diffusion and microdilution assays. The cytotoxicity of the AgNPs was investigated on a rat
macrophage (RAW 264.7) cells using MTT assay. Both the RPE and GPE were capable of synthesizing
the AgNPs at high temperatures (70 and 100 C). The AgNPs exhibited antibacterial activity against the
test strains, and also had low toxicity towards the RAW 264.7 cells. Thus, the synthesized AgNPs have a
potentially viable use in bio-applications for treatment of bacterial infections.
Description
Keywords
Anthocyanins, Forelle pears, Nutraceuticals, Antibacterial agents
Citation
Sohail Simon, Nicole Remaliah Samantha Sibuyi, Adewale Oluwaseun Fadaka, Mervin Meyer, Abram Madimabe Madiehe & Marlene Geraldine du Preez (2021) The antimicrobial activity of biogenic silver nanoparticles synthesized from extracts of Red and Green European pear cultivars, Artificial Cells, Nanomedicine, and Biotechnology, 49:1, 614-625, DOI: 10.1080/21691401.2021.1980884