Neuroprotective activities of Boophone haemanthoides (amaryllidaceae) extract and its chemical constituents
| dc.contributor.author | Ibrakaw, Abobaker S. | |
| dc.contributor.author | Omoruyi, Sylvester I. | |
| dc.contributor.author | Ekpo, Okobi E. | |
| dc.date.accessioned | 2020-12-07T07:07:24Z | |
| dc.date.available | 2020-12-07T07:07:24Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | Parkinson’s disease (PD) is a neurodegenerative condition that progresses as age increases, and some of its major symptoms include tremor and postural and movement-related difficulties. To date, the treatment of PD remains a challenge because available drugs only treat the symptoms of the disease or possess serious side effects. In light of this, new treatment options are needed; hence, this study investigates the neuroprotective effects of an organic Boophone haemanthoides extract (BHE) and its bioactive compounds using an in vitro model of PD involving the toxin 1-methyl-4-phenylpyridinium (MPP+) and SH-SY5Y neuroblastoma cells. | en_US |
| dc.identifier.citation | Ibrakaw, A. S. et al. (2020). Neuroprotective Activities of Boophone haemanthoides (Amaryllidaceae) Extract and Its Chemical Constituents. Molecules (Basel, Switzerland), 25(22) | en_US |
| dc.identifier.issn | 1420-3049 | |
| dc.identifier.uri | https://doi.org/10.3390/molecules25225376 | |
| dc.identifier.uri | http://hdl.handle.net/10566/5482 | |
| dc.language.iso | en | en_US |
| dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | en_US |
| dc.subject | Amaryllidaceae | en_US |
| dc.subject | Boophone haemanthoides | en_US |
| dc.subject | Alkaloids; terpenoids | en_US |
| dc.subject | Parkinson’s disease | en_US |
| dc.subject | Neuroprotection | en_US |
| dc.title | Neuroprotective activities of Boophone haemanthoides (amaryllidaceae) extract and its chemical constituents | en_US |
| dc.type | Article | en_US |