Adherence to isoniazid preventive therapy among child contacts in Rwanda: A mixed-methods study
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Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
Public Library of Science
Abstract
The World Health Organization recommends isoniazid preventive therapy (IPT) for six months for child contacts without tuberculosis (TB), who are exposed to an adult with active TB. The effectiveness of IPT depends on 80% or greater adherence to medication. In the current study, we assessed IPT adherence and explored barriers to and facilitators of adherence among eligible child contacts in Kigali, Rwanda.A mixed method study design was used to prospectively assess adherence to IPT among eligible child contacts and its associated factors through a quantitative, observational cohort study, and to explore barriers to and facilitators of adherence to IPT through a descriptive qualitative study.
Description
Keywords
Isoniazid, Therapy, Child contacts, Rwanda, Tuberculosis (TB), Poverty and relocation
Citation
Birungi, F.M. et al., 2019). Adherence to isoniazid preventive therapy among child contacts in Rwanda: A mixed-methods study. PLoS ONE, 14(2), 1–16. https://doi.org/10.1371/journal.pone.0211934