Electrochemical poly(ProDOT) dendritic DNA aptamer biosensor for signalling interferon gamma (IFN-ɣ) TB biomarker
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Date
2017
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
University of the Western Cape
Abstract
Tuberculosis (TB) is an infectious disease that, despite all efforts devoted towards its
eradication, remains a threat to many countries including South Africa. Current diagnostic
assays do offer better performance than the conventional sputum smear microscopy and
tuberculin skin tests. However, these assays have been proven to be affected by various factors
including the condition of an individual's immune system and vaccination history. By far,
electrochemical biosensors are amongst the currently investigated techniques to address the
shortcomings associated with these diagnostics.
Description
Philosophiae Doctor - PhD
Keywords
Aptasensor, Bisphenol A, Conducting polymer nanocomposites, Disease biomarker, DNA aptamer, Electrochemical impedance spectroscopy, Endocrine disrupting compounds, Gold nanoparticles, Immune system, Interferon gamma, Limit of detection, Pleural fluid, Poly(3,4-propylenedioxythiophene), Tuberculosis
Citation
Sidwaba, Unathi. ( 2017). Electrochemical poly(ProDOT) dendritic DNA aptamer biosensor for signalling interferon gamma (IFN-ɣ) TB biomarker. PhD. University of the Western Cape