Advances in nanotechnology towards development of silver nanoparticle-based wound-healing agents

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dc.contributor.authorNqakala, Zimkhitha B.
dc.contributor.authorSibuyi, Nicole R. S.
dc.contributor.authorFadaka, Adewale O.
dc.date.accessioned2021-11-11T11:51:40Z
dc.date.available2021-11-11T11:51:40Z
dc.date.issued2021
dc.description.abstractSince antiquity, silver-based therapies have been used in wound healing, wound care and management of infections to provide adequate healing. These therapies are associated with certain limitations, such as toxicity, skin discolouration and bacterial resistance, which have limited their use. As a result, new and innovative wound therapies, or strategies to improve the existing therapies, are sought after. Silver nanoparticles (AgNPs) have shown the potential to circumvent the limitations associated with conventional silver-based therapies as described above. AgNPs are effective against a broad spectrum of microorganisms and are less toxic, effective at lower concentrations and produce no skin discolouration. Furthermore, AgNPs can be decorated or coupled with other healingpromoting materials to provide optimum healing. This review details the history and impact of silver-based therapies leading up to AgNPs and AgNP-based nanoformulations in wound healing. It also highlights the properties of AgNPs that aid in wound healing and that make them superior to conventional silver-based wound treatment therapies.en_US
dc.identifier.citationNqakala, Z. B. et al. (2021). Advances in nanotechnology towards development of silver nanoparticle-based wound-healing agents. International Journal of Molecular Sciences, 22(20),11272en_US
dc.identifier.issn1422-0067
dc.identifier.urihttps://doi.org/10.3390/ijms222011272
dc.identifier.urihttp://hdl.handle.net/10566/7005
dc.language.isoenen_US
dc.publisherMPDIen_US
dc.subjectAntimicrobial agentsen_US
dc.subjectNanotechnologyen_US
dc.subjectSilver nanoparticlesen_US
dc.subjectWound healingen_US
dc.subjectSilver-based therapiesen_US
dc.titleAdvances in nanotechnology towards development of silver nanoparticle-based wound-healing agentsen_US
dc.typeArticleen_US

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