Frequency of CCR2V64I and CCR5Δ32 host genes and their association with HIV infection among pregnant women from Harare, Zimbabwe

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dc.contributor.advisorVan Wyk, Brian
dc.contributor.authorSoko, White
dc.contributor.otherSchool of Public Health
dc.contributor.otherFaculty of Community and Health Sciences
dc.date.accessioned2013-08-02T13:52:09Z
dc.date.accessioned2026-06-10T08:37:41Z
dc.date.available2011/10/20 11:40
dc.date.available2011/10/20
dc.date.available2013-08-02T13:52:09Z
dc.date.available2026-06-10T08:37:41Z
dc.date.issued2010
dc.descriptionMagister Public Health - MPHen_US
dc.description.abstractAim: To determine and compare the prevalence of CCR5-Δ32 and CCRV64I genes in HIV positive and HIV negative population of pregnant women from Harare, in Zimbabwe. Results: The proportion of pregnant women with the homozygous CCR2V64I gene was 24.38% and this gene was two times more associated with HIV infection than in those without it ( RR= 2.32, 95% CI-1.38-3.92). No CCR5-Δ32 deletion was detected in the studied population. Conclusion: The homozygous CCR2V64I gene and STIs were more prevalent in HIV infected pregnant women than in uninfected pregnant women and no homozygousCCR5-Δ32 gene was detected in this study.en_US
dc.description.countrySouth Africa
dc.identifier.urihttps://hdl.handle.net/10566/23214
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectHIV in pregnant womenen_US
dc.subjectHost genetic factorsen_US
dc.subjectGene polymorphismen_US
dc.subjectMutationen_US
dc.subjectProtective effecten_US
dc.subjectCCR5-Δ32en_US
dc.subjectCCR2V64en_US
dc.subjectVaccinesen_US
dc.subjectChemotherapeutic drugsen_US
dc.subjectZimbabween_US
dc.titleFrequency of CCR2V64I and CCR5Δ32 host genes and their association with HIV infection among pregnant women from Harare, Zimbabween_US
dc.typeThesisen_US

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