Potential beneficial effects of Tulbaghia violacea William Henry Harvey (Alliaceae) on cardiovascular system - A review

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Date

2015

Journal Title

Journal ISSN

Volume Title

Publisher

Pharmacotherapy Group, University of Benin

Abstract

Tulbaghia violacea William Henry Harvey (Harv. Alliaceae) is a small bulbous herb belonging to the family Alliaceae. It is used in South Africa to treat fever, colds, asthma, paralysis, and hypertension. Meanwhile, cardiovascular disease accounts for about 30 % of total global death, with most of these deaths occurring in low and middle-income countries. Furthermore, people in low-income countries are still largely dependent on plants in their surroundings for both prophylaxis and treatment of diseases, partly due to limited access to and cost of pharmaceuticals, and folkloric evidence of the potency of medicinal plants and/or local belief systems. Therefore, the present review aims to proffer possible ways by which T. violacea may improve cardiovascular outcomes. An extensive and systematic review of the literature was carried out, and relevant findings presented in this review. There is evidence that T. violacea may modulate the renin-angiotensin system, the autonomic nervous system, oxidative stress and haemostasis, with resultant protection of the cardiovascular system in both health and disease.

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Keywords

Tulbaghia violacea, Hypertension, Renin-angiotensin aldosterone system, Blood pressure, Cardiovascular disease, Autonomic nervous system, Oxidative stress, Haemostasis, Treatment, Tulbaghia violacea William Henry Harvey (Harv. Alliaceae)

Citation

Ismaila, R. et al. (2015). Potential beneficial effects of Tulbaghia violacea William Henry Harvey (Alliaceae) on cardiovascular system - A review. Tropical Journal of Pharmaceutical Research, 14 (6): 1111-1117