The influence of maternal nicotine exposure on neonatal rat trachea development and alveoli status
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Date
2000
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
University of the Western Cape
Abstract
The aim of this study was to determine the effect of maternal nicotine exposure on
the status of the rat tracheal development as well as the rat lung of 7 to 42 day old
offspring. Wistar dams were injected subcutaneously, using a dosage of 1 mg
nicotine/kg body mass/day, and treatment commenced 7 days after conception. The
morphological and morphometric data were used to evaluate any damage or change
in the structure of the trachea and lungs due to maternal nicotine exposure. Three
techniques were used namely, light microscopy, scanning electron microscopy and
transmission electron microscopy. Both morphological status and morphometric data
were obtained from the sample animals.
Description
>Magister Scientiae - MSc
Keywords
Maternal nicotine, Morphology, Biology, Biodiversity