Microtubular dysfunction and male infertility

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dc.contributor.authorGunes, Sezgin
dc.contributor.authorSengupta, Pallav
dc.contributor.authorHenkel, Ralf
dc.contributor.authorAlguraigari, Aabed
dc.contributor.authorSinigaglia, Mariana Marques
dc.contributor.authorKayal, Malik
dc.contributor.authorJoumah, Ahmad
dc.contributor.authorAgarwal, Ashok
dc.date.accessioned2018-11-05T07:17:41Z
dc.date.available2018-11-05T07:17:41Z
dc.date.issued2018
dc.description.abstractMicrotubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of sperm. Also, microtubule based structures such as axoneme and manchette are crucial for sperm head and tail formation. This review (a) presents a concise, yet detailed structural overview of the microtubules, (b) analyses the role of microtubule structures in various male reproductive functions, and (c) presents the association of microtubular dysfunctions with male infertility. Considering the immense importance of microtubule structures in the formation and maintenance of physiological functions of sperm cells, this review serves as a scientific trigger in stimulating further male infertility research in this direction.en_US
dc.identifier.citationGunes, S. et al. (2018). Microtubular dysfunction and male infertility. The World Journal of Men's Health, 2018.en_US
dc.identifier.issn2287-4208
dc.identifier.urihttps://doi.org/10.5534/wjmh.180066
dc.identifier.urihttp://hdl.handle.net/10566/4180
dc.language.isoenen_US
dc.privacy.showsubmitterFALSE
dc.publisherKorean Society for Sexual Medicine and Andrologyen_US
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.status.ispeerreviewedTRUE
dc.subjectAxonemeen_US
dc.subjectMale infertilityen_US
dc.subjectKartagener syndromeen_US
dc.subjectMicrotubule-associated proteinsen_US
dc.titleMicrotubular dysfunction and male infertilityen_US
dc.typeArticleen_US

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