Chemical and biological evaluation of palythoa tuberculosa collected from the red sea

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dc.contributor.advisorMohammed, Ahmed
dc.contributor.advisorMeyer, Mervin
dc.contributor.authorElbagory, Abdulrahman Mohammed
dc.date.accessioned2015-05-05T08:57:11Z
dc.date.accessioned2024-05-09T10:50:28Z
dc.date.available2015-05-05T08:57:11Z
dc.date.available2024-05-09T10:50:28Z
dc.date.issued2015
dc.descriptionMasters of Scienceen_US
dc.description.abstractA chemical study on the total extract of the zoanthid Palythoa tuberculosa, collected from the Red Sea, resulted in the isolation of seven polyhydroxylated sterols viz: palysterols A-G, six of which are new. Their chemical structures were elucidated on the basis of their 1D and 2D NMR and MS spectroscopic data. Palysterols B and G demonstrated cytotoxic activity on three human cancer cell lines (MCF-7, HeLa, and HT- 29). Palysterol G, in particular, was able to induce apoptosis in breast adenocarcinoma(MCF-7) cellsen_US
dc.identifier.urihttps://hdl.handle.net/10566/14524
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectMarine natural producten_US
dc.subjectRed Seaen_US
dc.subjectPalythoa tuberculosaen_US
dc.subjectPolyhydroxylated sterolsen_US
dc.subjectCytotoxicityen_US
dc.subjectApoptosisen_US
dc.titleChemical and biological evaluation of palythoa tuberculosa collected from the red seaen_US
dc.typeThesisen_US

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Magister Scientiae - MSc (Chemistry)