Philosophiae Doctor - PhD (Chemistry)

Permanent URI for this collection

https://hdl.handle.net/10566/14656

Browse

Browsing by Subject "Acetylcholinesterase"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Mercaptobenzothiazole-on-Gold Biosensor Systems for Organophosphate and Carbamate Pesticide Compounds
    (University of the Western Cape, 2007) Somerse, Vernon Sydwill; Iwuoha, Emmanuel; Baker, P.G.L.; Dept. of Chemistry; Faculty of Science
    This study firstly reports the development, characterisation, and application of thick-film acetylcholinesterase (AChE) biosensors based on a gold electrode modified with a mercaptobenzothiazole (MBT) self-assembled monolayer and either poly(omethoxyaniline) (POMA) or poly(2,5-dimethoxyaniline) (PDMA) in the presence of polystyrene(4-sulphonic acid) (PSSA). The Au/MBT/POMA-PSSA/AChE and Au/MBT/PDMA-PSSA/AChE biosensors were then applied to successfully detect standard organophosphorous and carbamate pesticides in a 0.1 M phosphate buffer, 0.1 M KCl (pH 7.2) solution. Secondly, it reports the construction of the Au/MBT/PANI/AChE/PVAc thick-film biosensor for the determination of certain organophosphate and carbamate pesticide solutions in selected aqueous organic solvent solutions.