Browsing by Author "Yvette, Mofenge Opute"

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    Novel adamantane-chloroquinolin conjugates to overcome plasmodium falciparum chloroquine resistance
    (University of the Western Cape, 2017) Yvette, Mofenge Opute; Joubert, Jacques; Malan, Sarel
    Malaria poses devastating health and socioeconomic outcomes on global health especially among pregnant women and children below the age of 5 in endemic areas. This is exacerbated by Plasmodium falciparum resistance to available antimalarial drugs, especially chloroquine (CQ), which was the drug of choice for many years against the blood stage of malaria.