Browsing by Author "Tareq, Abu Saleh"
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Item Prevalence of interleukin-1 polymorphisms and its association with periodontal disease status in the Xhosa population of South Africa(University of the Western Cape, 2007) Tareq, Abu Saleh; Stephen, L.X.G.; Dept. of Oral Medicine and Periodontics; Faculty of SciencePeriodontitis is a bacterially induced chronic inflammatory disease that destroys the supporting tissues of teeth. Clinical observations and experimental evidence indicates that there is a genetic influence of risk factors for periodontitis. A specific pattern of IL-1 polymorphisms (known as the composite IL-1 genotype) has been found to influence the severity of chronic periodontitis. The objective of this study was to evaluate the association between the IL-1 gene polymorphisms and the severity of periodontal disease in a selected Xhosa ppopulation of South africa.