Browsing by Author "Myer, Landon"

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    An approach to developing a prediction model of fertility intent among HIV-positive women and men in Cape Town, South Africa: a case study
    (Springer, 2017) Bai, Dan; Leu, Cheng-Shiun; Mantell, Joanne E.; Exner, Theresa M.; Cooper, Diane; Hoffman, Susie; Kelvin, Elizabeth A.; Myer, Landon; Constant, Debbie; Moodley, Jennifer
    As a ‘case-study’ to demonstrate an approach to establishing a fertility-intent prediction model, we used data collected from recently diagnosed HIV-positive women (N = 69) and men (N = 55) who reported inconsistent condom use and were enrolled in a sexual and reproductive health intervention in public sector HIV care clinics in Cape Town, South Africa. Three theoretically-driven prediction models showed reasonable sensitivity (0.70–1.00), specificity (0.66–0.94), and area under the receiver operating characteristic curve (0.79–0.89) for predicting fertility intent at the 6-month visit. A k-fold cross-validation approach was employed to reduce bias due to over-fitting of data in estimating sensitivity, specificity, and area under the curve. We discuss how the methods presented might be used in future studies to develop a clinical screening tool to identify HIV-positive individuals likely to have future fertility intent and who could therefore benefit from sexual and reproductive health counselling around fertility options.
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    Task-sharing of psychological treatment for antenatal depression in Khayelitsha, South Africa: Effects on antenatal and postnatal outcomes in an individual randomised controlled trial
    (Elsevier, 2020) Lund, Crick; Schneider, Marguerite; Garman, Emily C; Davies, Thandi; Munodawafa, Memory; Honikman, Simone; Bhana, Arvin; Bassf, Judith; Bolton, Paul; Dewey, Michael; Joska, John; Kagee, Ashraf; Myer, Landon; Petersen, Inge; Prince, Martin; Stein, Dan J; Tabana, Hanani; Thornicroft, Graham; Tomlinson, Mark; Hanlon, Charlotte; Alem, Atalay; Susser, Ezra
    The study's objective was to determine the effectiveness of a task-sharing psychological treatment for perinatal depression using non-specialist community health workers. A double-blind individual randomised controlled trial was conducted in two antenatal clinics in the peri-urban settlement of Khayelitsha, Cape Town. Adult pregnant women who scored 13 or above on the Edinburgh Postnatal Depression rating Scale (EPDS) were randomised into the intervention arm (structured six-session psychological treatment) or the control arm (routine antenatal health care and three monthly phone calls). The primary outcome was response on the Hamilton Depression Rating Scale (HDRS) at three months postpartum (minimum 40% score reduction from baseline) among participants who did not experience pregnancy or infant loss (modified intention-to-treat population) (registered on Clinical Trials: NCT01977326).